Guantánamo is a municipality and city in southeast Cuba and capital of Guantánamo Province. Guantánamo is served by the Caimanera por…Guantánamo is a municipality and city in southeast Cuba and capital of Guantánamo Province. Guantánamo is served by the Caimanera port near the site of a U.S. naval base. The area produces sugarcane and cotton wool. These are traditional parts of the economy.