Oddsmakers expect the Tennessee Titans (3-11) to put up a fight in their attempt to halt their three-game losing streak, as they are just 3.5-point underdogs in a matchup against the Indianapolis

Pete Prisco is picking the Colts to win by a touchdown. While others think that last week’s loss will rollover into this game against Tennessee, Prisco thinks the opposite, mentioning that the Colts defense did a lot of good things last week, resulting in a bounce-back win.

Our experts' predictions are in for Tennessee Titans vs. Indianapolis Colts on Sunday. Here's who our experts are picking to win the Week 16 NFL game.

See who experts around the league are taking in a Week 16 matchup between the Tennessee Titans and Indianapolis Colts.

Despite their 34-27 loss to the Los Angeles Chargers on Thursday Night Football, the Denver Broncos can still clinch a spot in the 2024 NFL playoffs this weekend. The Broncos will clinch a Wild Card spot in the postseason if three games go their way on Sunday.

Will Levis had a miserable day. He had a fumble, interception and another interception in a span of eight plays. Later, he threw a pick 6 and was benched. Levis made some strides recently, but Sunday was a reminder that the Titans probably shouldn’t trust him as the 2025 starter.

The Indianapolis Colts Week 15 loss to the Denver Broncos put their playoff hopes on life support.They are still holding on to a slim chance to punch their ticket to the AFC playoffs, but they no longer control their own destiny.