The NFL has two Saturday games in Week 16. Leading off at 1 p.m. ET, we have the Houston Texans on the road against the Kansas City Chiefs. The game will air on NBC.

Pete Prisco is picking the Colts to win by a touchdown. While others think that last week’s loss will rollover into this game against Tennessee, Prisco thinks the opposite, mentioning that the Colts defense did a lot of good things last week, resulting in a bounce-back win.

Patrick Mahomes (high ankle sprain) will “most likely” play Saturday against the Houston Texans in the first Saturday game of the 2024 season, according to coach Andy Reid. Mahomes’ status has been the most-tracked storyline of the week for Chiefs' fans and NFL bettors alike.

The winner of the Steelers-Ravens game on Saturday likely wins the AFC North, and the loser is likely to face the Chargers in the playoffs.

Week 16 features four days of NFL action as teams jockey, with varying degrees of desperation, for playoff positioning.

Star cornerback Derek Stingley Jr. will likely match up against five-time Pro Bowler DeAndre Hopkins, which could funnel more passes to Worthy’s side of the field. Oddsmakers aren’t expecting much from Worthy, pegging his receiving yards total well below his recent production.

We’re looking at who the NFL experts are picking in the Philadelphia Eagles game against the Washington Commanders in Week 16

The NFL Week 16 schedule is sure to be a little wacky, with a marquee slate on Saturday giving way to a fairly uninspiring setup for Sunday.