Watch "49ers Now" with Matt Maiocco and Jennifer Lee Chan at 4 p.m. PT today from Santa Clara, streaming live on the NBC ...

Videos are auto-populated by an affiliate. This site has no control over the videos that appear above. The San Francisco ...

Watch "49ers Now" with Matt Maiocco and Jennifer Lee Chan at 4 p.m. PT today from Santa Clara, streaming live on the NBC ...

Brock Purdy has lost his fourth-quarter touch and the chip on his shoulder this season, as the 49ers (6-8) head to face the ...

Mike McDaniel spent five seasons on the San Francisco 49ers coaching staff before leaving to become the head coach of the ...

Brock Purdy is having a rough season. He's on the verge of signing a life-changing contract extension, and yet he also is the ...

The Miami Dolphins will host the San Francisco 49ers at Hard Rock Stadium on Sunday in a Week 16 showdown. Which five ...

The 49ers will have to start their fourth different running back this Sunday against the Miami Dolphins. That's because ...

San Francisco 49ers running back Isaac Guerendo appeared on Wednesday's injury report due to a hamstring issue sustained ...

San Francisco 49ers linebacker Dre Greenlaw made an inspiring return from an Achilles injury last week against the Los ...

The 49ers have gotten used to being shorthanded at running back this season and it looks like they'll be down another one in ...

The book on Brock Purdy is out. Play man-to-man coverage and he folds. He's still good against zone coverage -- this season, ...