The 49ers went after Guerendo in the draft because he reminded them a lot of Mostert, whom they'll face Sunday in Miami.

The San Francisco 49ers face the Miami Dolphins this weekend and the rookie running back is now a major doubt to take part.

Reporting emerged earlier on Thursday noting that 49ers running back Isaac Guerendo is unlikely to play in Sunday's game ...

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

ESPN insider Adam Schefter reported that San Francisco 49ers rookie running back Isaac Guerendo is unlikely to play against ...

Shanahan also hinted toward the rest of Williams’ 2024 season being in doubt. Also appearing on Wednesday’s injury report was ...

"Patrick Taylor Jr.is a fantasy football waiver wire pickup option at running back. Target him as a free agent add off ...

After losing RBs Christian McCaffrey, Jordan Mason and Elijah Mitchell to season-ending injuries, it now looks as if the ...

The 49ers will have to start their fourth different running back this Sunday against the Miami Dolphins. That's because ...

49ers running back Isaac Guerendo is unlikely to play against the Dolphins on Sunday, per ESPN's Adam Schefter. Guerendo is dealing with a hamstring injury, which is expected to keep him off the field ...

What’s going on with the 49ers? The post Will Isaac Guerendo Play vs. Dolphins? 49ers Announce Major Injury Ahead of Week 16 ...

Josh Inglis highlights his three favorite anytime touchdown props for NFL Week 16, including Ray Davis vs the Patriots.